diff --git a/include/qemu/qemu-plugin.h b/include/qemu/qemu-plugin.h
index 7c33e2a5887..1044fa7b14f 100644
--- a/include/qemu/qemu-plugin.h
+++ b/include/qemu/qemu-plugin.h
@@ -52,7 +52,11 @@ typedef uint64_t qemu_plugin_id_t;
  * The plugins export the API they were built against by exposing the
  * symbol qemu_plugin_version which can be checked.
  *
- * version 2: removed qemu_plugin_n_vcpus and qemu_plugin_n_max_vcpus
+ * version 2:
+ * - removed qemu_plugin_n_vcpus and qemu_plugin_n_max_vcpus
+ * - Remove qemu_plugin_register_vcpu_{tb, insn, mem}_exec_inline.
+ *   Those functions are replaced by *_per_vcpu variants, which guarantee
+ *   thread-safety for operations.
  */
 
 extern QEMU_PLUGIN_EXPORT int qemu_plugin_version;
@@ -309,25 +313,6 @@ enum qemu_plugin_op {
     QEMU_PLUGIN_INLINE_ADD_U64,
 };
 
-/**
- * qemu_plugin_register_vcpu_tb_exec_inline() - execution inline op
- * @tb: the opaque qemu_plugin_tb handle for the translation
- * @op: the type of qemu_plugin_op (e.g. ADD_U64)
- * @ptr: the target memory location for the op
- * @imm: the op data (e.g. 1)
- *
- * Insert an inline op to every time a translated unit executes.
- * Useful if you just want to increment a single counter somewhere in
- * memory.
- *
- * Note: ops are not atomic so in multi-threaded/multi-smp situations
- * you will get inexact results.
- */
-QEMU_PLUGIN_API
-void qemu_plugin_register_vcpu_tb_exec_inline(struct qemu_plugin_tb *tb,
-                                              enum qemu_plugin_op op,
-                                              void *ptr, uint64_t imm);
-
 /**
  * qemu_plugin_register_vcpu_tb_exec_inline_per_vcpu() - execution inline op
  * @tb: the opaque qemu_plugin_tb handle for the translation
@@ -359,21 +344,6 @@ void qemu_plugin_register_vcpu_insn_exec_cb(struct qemu_plugin_insn *insn,
                                             enum qemu_plugin_cb_flags flags,
                                             void *userdata);
 
-/**
- * qemu_plugin_register_vcpu_insn_exec_inline() - insn execution inline op
- * @insn: the opaque qemu_plugin_insn handle for an instruction
- * @op: the type of qemu_plugin_op (e.g. ADD_U64)
- * @ptr: the target memory location for the op
- * @imm: the op data (e.g. 1)
- *
- * Insert an inline op to every time an instruction executes. Useful
- * if you just want to increment a single counter somewhere in memory.
- */
-QEMU_PLUGIN_API
-void qemu_plugin_register_vcpu_insn_exec_inline(struct qemu_plugin_insn *insn,
-                                                enum qemu_plugin_op op,
-                                                void *ptr, uint64_t imm);
-
 /**
  * qemu_plugin_register_vcpu_insn_exec_inline_per_vcpu() - insn exec inline op
  * @insn: the opaque qemu_plugin_insn handle for an instruction
@@ -597,24 +567,6 @@ void qemu_plugin_register_vcpu_mem_cb(struct qemu_plugin_insn *insn,
                                       enum qemu_plugin_mem_rw rw,
                                       void *userdata);
 
-/**
- * qemu_plugin_register_vcpu_mem_inline() - register an inline op to any memory access
- * @insn: handle for instruction to instrument
- * @rw: apply to reads, writes or both
- * @op: the op, of type qemu_plugin_op
- * @ptr: pointer memory for the op
- * @imm: immediate data for @op
- *
- * This registers a inline op every memory access generated by the
- * instruction. This provides for a lightweight but not thread-safe
- * way of counting the number of operations done.
- */
-QEMU_PLUGIN_API
-void qemu_plugin_register_vcpu_mem_inline(struct qemu_plugin_insn *insn,
-                                          enum qemu_plugin_mem_rw rw,
-                                          enum qemu_plugin_op op, void *ptr,
-                                          uint64_t imm);
-
 /**
  * qemu_plugin_register_vcpu_mem_inline_per_vcpu() - inline op for mem access
  * @insn: handle for instruction to instrument
diff --git a/plugins/api.c b/plugins/api.c
index 5fed50d9b09..e0af3c4a9e3 100644
--- a/plugins/api.c
+++ b/plugins/api.c
@@ -101,16 +101,6 @@ void qemu_plugin_register_vcpu_tb_exec_cb(struct qemu_plugin_tb *tb,
     }
 }
 
-void qemu_plugin_register_vcpu_tb_exec_inline(struct qemu_plugin_tb *tb,
-                                              enum qemu_plugin_op op,
-                                              void *ptr, uint64_t imm)
-{
-    if (!tb->mem_only) {
-        plugin_register_inline_op(&tb->cbs[PLUGIN_CB_INLINE],
-                                  0, op, ptr, imm);
-    }
-}
-
 void qemu_plugin_register_vcpu_tb_exec_inline_per_vcpu(
     struct qemu_plugin_tb *tb,
     enum qemu_plugin_op op,
@@ -138,16 +128,6 @@ void qemu_plugin_register_vcpu_insn_exec_cb(struct qemu_plugin_insn *insn,
     }
 }
 
-void qemu_plugin_register_vcpu_insn_exec_inline(struct qemu_plugin_insn *insn,
-                                                enum qemu_plugin_op op,
-                                                void *ptr, uint64_t imm)
-{
-    if (!insn->mem_only) {
-        plugin_register_inline_op(&insn->cbs[PLUGIN_CB_INSN][PLUGIN_CB_INLINE],
-                                  0, op, ptr, imm);
-    }
-}
-
 void qemu_plugin_register_vcpu_insn_exec_inline_per_vcpu(
     struct qemu_plugin_insn *insn,
     enum qemu_plugin_op op,
@@ -175,15 +155,6 @@ void qemu_plugin_register_vcpu_mem_cb(struct qemu_plugin_insn *insn,
                                 cb, flags, rw, udata);
 }
 
-void qemu_plugin_register_vcpu_mem_inline(struct qemu_plugin_insn *insn,
-                                          enum qemu_plugin_mem_rw rw,
-                                          enum qemu_plugin_op op, void *ptr,
-                                          uint64_t imm)
-{
-    plugin_register_inline_op(&insn->cbs[PLUGIN_CB_MEM][PLUGIN_CB_INLINE],
-                              rw, op, ptr, imm);
-}
-
 void qemu_plugin_register_vcpu_mem_inline_per_vcpu(
     struct qemu_plugin_insn *insn,
     enum qemu_plugin_mem_rw rw,
diff --git a/plugins/qemu-plugins.symbols b/plugins/qemu-plugins.symbols
index 0d8141b85f1..a9fac056c7f 100644
--- a/plugins/qemu-plugins.symbols
+++ b/plugins/qemu-plugins.symbols
@@ -27,16 +27,13 @@
   qemu_plugin_register_vcpu_idle_cb;
   qemu_plugin_register_vcpu_init_cb;
   qemu_plugin_register_vcpu_insn_exec_cb;
-  qemu_plugin_register_vcpu_insn_exec_inline;
   qemu_plugin_register_vcpu_insn_exec_inline_per_vcpu;
   qemu_plugin_register_vcpu_mem_cb;
-  qemu_plugin_register_vcpu_mem_inline;
   qemu_plugin_register_vcpu_mem_inline_per_vcpu;
   qemu_plugin_register_vcpu_resume_cb;
   qemu_plugin_register_vcpu_syscall_cb;
   qemu_plugin_register_vcpu_syscall_ret_cb;
   qemu_plugin_register_vcpu_tb_exec_cb;
-  qemu_plugin_register_vcpu_tb_exec_inline;
   qemu_plugin_register_vcpu_tb_exec_inline_per_vcpu;
   qemu_plugin_register_vcpu_tb_trans_cb;
   qemu_plugin_reset;
